博川报道：美国国家精神卫生研究所（NIMH）正在发起一项大规模的研究项目,以探讨针对慢性精神分裂症是否采用发病早期积极的、个性化的、整合各种不同的治疗方法治疗,这将减轻症状和阻止病情的逐渐恶化.
　　早期精神分裂症恢复项目(RAISE)是由NIMH资助的,美国的恢复和再投资基金(ARRA)对其也有资助.RAISE是《恢复法案》能够加速公共卫生问题解决和加速科研进展从而使公民潜在收益的典范.
   “这项新举措将帮助我们确定是否从最初就开始干预并采用不同的治疗和康复方法,并持续一段时间,从而使更多精神分裂症患者重返工作和学校,” NIH主任托马斯·塞尔博士说“此外,正在被测试的干预方式从开始设计到现实的卫生康复方式采用,是很容易实现的,也会很快被用于实践中.“
    尽管有温和有效的治疗,如抗精神病药和各种心理干预,精神分裂症患者直到已经确立为反复发作的精神病才得到治疗,导致昂贵的住院花费、甚至长期致残.精神分裂症患者常常失业,无家可归,或者遭遇监禁,给个人,家庭,以及整个社区带来很大的负担.

博川推荐原文检索：
【Abstract】
  Major NIMH Research Project to Test Approaches to Altering the Course of Schizophrenia
Recovery Act Funds Will Support First Phase of Project

  The National Institute of Mental Health (NIMH) is launching a large-scale research project to explore whether using early and aggressive treatment, individually targeted and integrating a variety of different therapeutic approaches, will reduce the symptoms and prevent the gradual deterioration of functioning that is characteristic of chronic schizophrenia.
  The Recovery After an Initial Schizophrenia Episode (RAISE) project is being funded by NIMH with additional support from the American Recovery and Reinvestment Act (ARRA). RAISE is a model example of how money from the Recovery Act can accelerate science related to public health problems and potentially benefit those citizens most in need.
  "This new initiative will help us determine whether intervention that is started early, incorporates diverse treatment and rehabilitation approaches, and is sustained over time, can make it possible for more people with schizophrenia to return successfully to work and school," said NIMH Director Thomas R. Insel, M.D. "Moreover, the interventions being tested will be designed from the outset to be readily adopted in real-world health care settings and quickly put into practice."
  Despite the availability of moderately effective treatments, such as antipsychotic medications and various psychosocial interventions, people with schizophrenia often do not receive treatment until the disease is already well-established, with recurrent episodes of psychosis, resulting in costly multiple hospitalizations and disabilities that can last for decades. Periods of unemployment, homelessness, and incarceration are common, making schizophrenia a costly disease for individuals, their families, and the community at large.
  原文链接"A key step for the future will be to identify the cellular pathways that are affected by these cyclic peptide原: http://www.nih.gov/news/health/jul2009/nimh-21.htm
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