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在妇产科腹腔镜手术中评价血液中脂质过氧化反应速率和抗氧化剂的意义

发布时间 2009-08-05 浏览量 作者: 无 来源: 生物无忧

    在妇科子宫肌瘤手术中对脂质过氧化反应(LPO)速率和红细胞抗氧化物(EAOD)进行了研究.手术前发现高的LPO速率和降低的VE 水平,在手术后发现LPO速率增加和VE 浓度减少,在术后5-7天后该数据参数开始回复.本研究确认谷胱甘肽-S-转移酶在EAOD系统中起了关键的作用,它相当于该系统的中枢.

1: Klin Lab Diagn. 2009 Jun;(6):37-9
  Evaluation of the rate of lipid peroxidation and antioxidant defense in blood during gynecological laparoscopic operations]
[Article in Russian]
[No authors listed]
  The impact of gynecological operations on the rate of lipid peroxidation (LPO) and erythrocytic antioxidant defense (EAOD) was studied in women with uterine myoma. The higher rate of LPO and the decreased level of vitamin E were preoperatively found. A further increase in LPO activity and a reduction in vitamin E concentrations were observed 1-4 days after surgery. Recovery of the study parameters was seen on days 5-7 postoperatively. The enzyme glutathione-S-transferase was ascertained to play a pivotal role in the EAOD system.
  PMID: 19645117 [PubMed - in process]

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